Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance

Recent News

CrossBridge Bio Awarded $15 Million CPRIT Grant to Advance CBB-120, Its Lead Dual-Payload ADC Targeting TROP-2, Into the Clinic

CrossBridge Bio, a biotechnology company pioneering next-generation dual-payload antibody-drug conjugates (ADCs) that have the potential to deliver safer, more durable responses for patients, including those resistant to approved ADC therapies, today announced it has been awarded a $15 million grant from the Cancer Prevention and Research Institute of Texas (CPRIT). The award will support completion of IND-enabling activities and advancement of CBB-120, the company’s lead TROP-2 targeted TOP1i/ATRi dual-payload ADC, into first-in-human studies.

CrossBridge Bio Wins “Best Drug Developer” at 2025 World ADC Awards

HOUSTON--(BUSINESS WIRE)--CrossBridge Bio, a biopharmaceutical company pioneering next-generation dual-payload antibody-drug conjugates (ADCs) that have the potential to deliver safer more durable responses in patients, including those resistant to approved ADC therapies, today announced that it has been named the Winner of “Best Drug Developer” at the 2025 World ADC Awards.

CrossBridge Bio, Inc. Receives $2.6M in Non-Dilutive Funding from CPRIT to Advance, CBB-120, a Next-Generation Dual-Payload Antibody-Drug Conjugate for the Treatment of TROP-2+ Solid Tumors 

CrossBridge Bio, Inc. proudly announces the receipt of a substantial competitive non-dilutive grant from the Cancer Prevention and Research Institute of Texas (CPRIT). This grant marks a significant milestone in CrossBridge's mission to propel its innovative dual-payload ADC platform and potential best-in-class TROP2 program, CBB-120, to IND-enabling studies.